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in Fig. S3. Rows labeled 1 show the re-projections of our reconstruction whereas rows labeled two show the ab initio classes averages. For every single re-projection, the corresponding ab inito calculated classes are extremely similar, confirming our 3D reconstruction. Supporting Details tions in the EM 3D reconstruction plus the ab-initio obtained classes . 196 re-projections of our 3D reconstruc
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